Tuning-primer.sh Results, How To Act On Them

Quote:

MySQL Version 4.1.22-standard i686

Uptime = 0 days 0 hrs 4 min 15 sec
Avg. qps = 17
Total Questions = 4479
Threads Connected = 1

Warning: Server has not been running for at least 48hrs.
It may not be safe to use these recommendations

To find out more information on how each of these
runtime variables effects performance visit:
[url]

SLOW QUERIES
Current long_query_time = 10 sec.
You have 1 out of 4491 that take longer than 10 sec. to complete
The slow query log is NOT enabled.
Your long_query_time may be too high, I typically set this under 5 sec.

WORKER THREADS
Current thread_cache_size = 128
Current threads_cached = 6
Current threads_per_sec = 0
Historic threads_per_sec = 0
Your thread_cache_size is fine

MAX CONNECTIONS
Current max_connections = 2000
Current threads_connected = 1
Historic max_used_connections = 7
The number of used connections is 0% of the configured maximum.
You are using less than 10% of your configured max_connections.
Lowering max_connections could help to avoid an over-allocation of memory
See "MEMORY USAGE" section to make sure you are not over-allocating

MEMORY USAGE
Max Memory Ever Allocated : 96 M
Configured Max Per-thread Buffers : 10 G
Configured Max Global Buffers : 58 M
Configured Max Memory Limit : 10 G
Total System Memory : 3.95 G

Max memory limit exceeds 85% of total system memory

KEY BUFFER
Current MyISAM index space = 78 M
Current key_buffer_size = 16 M
Key cache miss rate is 1 : 735
Key buffer fill ratio = 8.00 %
Your key_buffer_size seems to be too high.
Perhaps you can use these resources elsewhere

QUERY CACHE
Query cache is enabled
Current query_cache_size = 32 M
Current query_cache_used = 4 M
Current query_cach_limit = 1 M
Current Query cache fill ratio = 14.83 %
Your query_cache_size seems to be too high.
Perhaps you can use these resources elsewhere
MySQL won't cache query results that are larger than query_cache_limit in size

SORT OPERATIONS
Current sort_buffer_size = 2 M
Current record/read_rnd_buffer_size = 256 K
Sort buffer seems to be fine

JOINS
Current join_buffer_size = 1.00 M
You have had 0 queries where a join could not use an index properly
Your joins seem to be using indexes properly

OPEN FILES LIMIT
Current open_files_limit = 10000 files
The open_files_limit should typically be set to at least 2x-3x
that of table_cache if you have heavy MyISAM usage.
Your open_files_limit value seems to be fine

TABLE CACHE
Current table_cache value = 1024 tables
You have a total of 721 tables
You have 93 open tables.
The table_cache value seems to be fine

TEMP TABLES
Current max_heap_table_size = 16 M
Current tmp_table_size = 32 M
Of 212 temp tables, 0% were created on disk
Effective in-memory tmp_table_size is limited to max_heap_table_size.
Created disk tmp tables ratio seems fine

TABLE SCANS
Current read_buffer_size = 1 M
Current table scan ratio = 17754 : 1
You have a high ratio of sequential access requests to SELECTs
You may benefit from raising read_buffer_size and/or improving your use of indexes.

TABLE LOCKING
Current Lock Wait ratio = 1 : 76
You may benefit from selective use of InnoDB.
If you have long running SELECT's against MyISAM tables and perform
frequent updates consider setting 'low_priority_updates=1'

how to make the changes in red? My server works good for awhile, but then gets REALLY REALLY slow.